The listed grades on this page are heterocyclic intermediates: N-(2-hydroxyethyl) morpholine, N-(2-chloroethyl) morpholine hydrochloride, N-(2-hydroxyethyl) piperidine and N-(2-chloroethyl) piperidine hydrochloride, released against assay as written on the TDS. They are chemical intermediates for further synthesis. They are not finished APIs and are not assumed pharmacopoeia excipients.
What pharma intermediates are
The listed grades on this page are heterocyclic intermediates: N-(2-hydroxyethyl) morpholine, N-(2-chloroethyl) morpholine hydrochloride, N-(2-hydroxyethyl) piperidine and N-(2-chloroethyl) piperidine hydrochloride, released against assay as written on the TDS. They are chemical intermediates for further synthesis. They are not finished APIs and are not assumed pharmacopoeia excipients.
Polyethylene glycols, polysorbates and selected esters used in pharma-adjacent wetting sit on their chemistry pages. An industrial PEG or polysorbate lot is not automatically a pharmacopoeia pack. Name the monograph, residual-solvent and microbial tests the receiving laboratory will run before a sample is labelled for that path. Dyna Glycols will not invent USP, EP, IP, FDA or FSSAI status for a catalogue surfactant.
How Dyna Glycols manufactures pharma intermediates
The named morpholine and piperidine derivatives are manufactured and released against assay, identity and the residual tests on the TDS (including the 99% and 98% cuts as listed). Custom assay windows are quoted after the existing specification.
PEG, polysorbate and ester grades for pharma-adjacent use are made on the same plants as the industrial grades, then documented to the tighter brief only when that brief is on the enquiry.
Typical grades in this range
The intermediates currently listed on this industry page are below. Open PEG, polysorbate and ester pages for those chemistries.
- N-(2-hydroxyethyl) morpholine (CAS 622-40-2)
- N-(2-chloroethyl) morpholine hydrochloride 99% (CAS 3647-69-6)
- N-(2-hydroxyethyl) piperidine 98% (CAS 3040-44-6)
- N-(2-chloroethyl) piperidine hydrochloride 98% (CAS 2008-75-5)
Where pharma intermediates are used
These heterocycles are used as building blocks in organic synthesis for pharmaceutical and related development. Specify the next reaction, residual-water or residual-chloride limits, and whether a hydrochloride salt or the free hydroxyethyl base is required.
If the need is a PEG 400, polysorbate 80 or glyceryl ester for a formulation brief, order from those chemistry pages and state the documentation path. Do not order a morpholine intermediate as a solubiliser.
How to specify pharma intermediates
Send CAS, assay, salt vs free base, residual solvents, water, and the tests the receiving QC will run. Attach the current competitor or in-house TDS if matching a lot.
For PEG or polysorbate pharma-adjacent enquiries, write the monograph name and dioxane/EO residual limits on the contact form. Those grades are sampled from the chemistry families, not from this short intermediate list.
Quality, documents and supply
Lots are released against assay and the identity tests on the TDS. SDS and COA follow verification. Chloroethyl hydrochlorides are handled as classified materials — follow the SDS and transport class.
Store dry and closed. Protect hydroxyethyl bases from moisture. Laboratory samples should be checked by the customer QC method before a bulk campaign.
Practical notes on pharma intermediates
Hydroxyethyl vs chloroethyl, and morpholine vs piperidine, are different molecules. Order by CAS.
Related pages: polyethylene glycol, polysorbates, glyceryl esters, food emulsifiers (for documentation discipline). Request SDS with the sample.
Avesta Pharma is referenced on some PEG pages for selected European PEG/macrogol supply. That path is not assumed for these heterocyclic intermediates.
Do not cite this page as a GMP-finished-dose manufacturer. Dyna Glycols is sampling chemical intermediates and industrial surfactants against named identity tests.
English is the source language for assay and CAS claims. Machine translation is not a specification.
Freeze assay and residual tests once a trial lot is approved.
Ordering and evaluating pharma intermediates
Send the application, the analytical window and the pack size when you request a laboratory sample of pharma intermediates. SDS, TDS and COA follow a short company check. Handle and store the grade as the SDS describes.
Next step
Need a specification for this chemistry?
Tell us the substrate, EO/PO moles and the application. We will confirm a catalogue grade or a custom batch.